ruvC Crossover junction endodeoxyribonuclease RuvC Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). lpg1287 Holliday junction resolvase RuvC 174 MTIILGIDPGSRVTGYGLIKESDRKIAYIDSGCIRTSNDTELSHKLLQIYDGICELMDHYSPTEVAIEQIFMHNNPNSALKLGHARGVAMVAAASHRAKIFEYSAREIKQSVVGYGAAEKDQVSHMVVELLQLNRAPQKDAADALAIAICHSHMRNGLSKLIGSRGTKRRRMRL Holliday junction nuclease RuvC RUVC_LEGPH